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CasNo: 28311-38-8
Molecular Formula: C11H15 N O2
Tolibut, also known as 3-(p-tolyl)-4-aminobutyric acid (or β-(4-methylphenyl)-GABA), is a GABA analogue developed in Russia. It is a chemical compound similar to phenibut, but with a 4-methyl substitution instead of a 4-chloro substitution found in baclofen.
InChI:InChI=1/C11H15NO2.ClH/c1-8-2-4-9(5-3-8)10(7-12)6-11(13)14;/h2-5,10H,6-7,12H2,1H3,(H,13,14);1H
WEIFANG YANGXU GROUP Co., Ltd was founded in 1996. More than 20 years full efforts, YANGXU chemical has grown to be a large enzyme peptide chemical enterprise, specializing in exploring, researching, manufacturing and marketing of industrial food chemical. We have 1 strain R & D center, 1 application research center and 2 modern manufacturing bases. Yangxu group is the member of China Biotech Fermentation Industry Association, and has been awarded as "Key Enterprise of China CHEMICAL Industry". Currently, YANGXU group has established 6 subsidiary companies and 30 offices in 32 cities, provinces and municipalities in China. Our products have been exported to more than 30 countries and regions. "littlestone" has become a leading brand of enzyme industry in China.
In the course of our exploration of the ...
4-(p-tolyl)pyrrolidin-2-one
4-amino-3-(p-tolyl)butanoic acid
Conditions | Yield |
---|---|
With hydrogenchloride; water; In water; for 16h; Reflux;
|
62% |
3-chloro-4-(p-tolyl)-1H-pyrrol-2(5H)-one
4-amino-3-(p-tolyl)butanoic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C
2: hydrogenchloride; water / water / 16 h / Reflux
With hydrogenchloride; sodium tetrahydroborate; water; nickel dichloride; In tetrahydrofuran; methanol; water;
|
4-methylphenylboronic acid
4-(p-tolyl)pyrrolidin-2-one