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Mirogabalin

  • Product Name: Mirogabalin
  • CasNo: 1138245-13-2
  • Purity:
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CasNo: 1138245-13-2

Molecular Formula: C12H19NO2

Manufacturer supply high quality Mirogabalin 1138245-13-2 with GMP standards

  • Molecular Formula:C12H19NO2
  • Molecular Weight:209.288
  • Boiling Point:357.5±15.0 °C(Predicted) 
  • PKA:4.65±0.10(Predicted) 
  • PSA:63.32000 
  • Density:1.104±0.06 g/cm3(Predicted) 
  • LogP:2.48270 

Mirogabalin is a gabapentinoid medication used to treat peripheral neuropathic pain, particularly diabetic peripheral neuropathy and postherpetic neuralgia. It works by binding to the α2δ subunit of voltage-gated calcium channels, similar to pregabalin, but with higher potency and a slower dissociation rate from the α2δ-1 subunit. This may lead to more sustained analgesia and potentially fewer central nervous system side effects compared to pregabalin.

WEIFANG YANGXU GROUP Co., Ltd was founded in 1996. More than 20 years full efforts, YANGXU chemical has grown to be a large enzyme peptide chemical enterprise, specializing in exploring, researching, manufacturing and marketing of industrial food chemical. We have 1 strain R & D center, 1 application research center and 2 modern manufacturing bases. Yangxu group is the member of China Biotech Fermentation Industry Association, and has been awarded as "Key Enterprise of China CHEMICAL Industry". Currently, YANGXU group has established 6 subsidiary companies and 30 offices in 32 cities, provinces and municipalities in China. Our products have been exported to more than 30 countries and regions. "littlestone" has become a leading brand of enzyme industry in China.

1138245-13-2 Relevant articles

Novel method for preparing Mirogabalin

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, (2020/05/30)

The invention relates to a novel method ...

METHOD FOR PRODUCING OPTICALLY ACTIVE BICYCLIC -AMINO ACID DERIVATIVE

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Paragraph 0170; 0171, (2015/05/26)

An object of the present invention is to...

BICYCLIC -AMINO ACID DERIVATIVE

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Page/Page column 45, (2010/06/17)

It is intended to provide a bicyclic γ-a...

1138245-13-2 Process route

(1R)-1-phenylethanaminium [(1R,5S,6S)-6-cyano-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetate

(1R)-1-phenylethanaminium [(1R,5S,6S)-6-cyano-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetate

DS-5565
1138245-13-2

DS-5565

Conditions
Conditions Yield
(1R)-1-phenylethanaminium [(1R,5S,6S)-6-cyano-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetate; With hydrogenchloride; In water; toluene;
With hydrogen; In tert-butyl methyl ether; at 20 ℃; for 3h; under 3040.2 Torr;
With potassium hydroxide; In tert-butyl methyl ether; water; for 0.5h;
88%
C<sub>12</sub>H<sub>19</sub>NO<sub>2</sub>*ClH

C12H19NO2*ClH

DS-5565
1138245-13-2

DS-5565

Conditions
Conditions Yield
C12H19NO2*ClH; With sulfuric acid; (S)-Mandelic acid; In methanol; isopropyl alcohol; at 40 ℃; for 0.5h;
With sodium hydroxide; In tetrahydrofuran; water; at 20 - 40 ℃; for 2h;
76%

1138245-13-2 Upstream products

  • 1138246-20-4
    1138246-20-4

    tert-butyl [(1R,5S,6S)-6-(tert-butoxycarbonylamino)methyl-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetate

  • 1235479-61-4
    1235479-61-4

    (1R,5S)-3-ethylbicyclo[3.2.0]hept-3-en-6-one

1138245-13-2 Downstream products

  • 1138245-21-2
    1138245-21-2

    [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate

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