Quality products make an important contribution to long-term revenue and profitability. Factory Sells Best Quality Azithromycin 83905-01-5 with GMP standards
1.What is the Azithromycin ?
Azithromycin in a 500-mg dose three times a week has been shown to yield a
60% reduction in inflammatory papules in 83% of patients enrolled in a 12-
week study. There is no associated pseudotumor cerebri and, therefore,
it can be used for an acne flare during early Accutane therapy.
Azithromycin is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.As for Gram-negative bacteria such as Haemophilus influenzae, Salmonella, E. coli, Shigella bacteria, it have strong antibacterial activity. And it is acid stable and well tolerated. It has a very good therapeutic effect on respiratory tract infections, skin and soft tissue infections, sexually transmitted diseases which are caused by sensitive bacteria.
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50-00-0,30525-89-4,61233-19-0
formaldehyd
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76801-85-9
9-Deoxo-9a-aza-9a-homoerythromycin A
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83905-01-5,92470-27-4
Zithromax(R)
Conditions
| Conditions |
Yield |
|
With
formic acid;
In
acetone;
at 30 - 55 ℃;
for 4h;
|
95%
|
|
formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A;
With
formic acid;
In
acetone;
at 40 - 45 ℃;
for 7 - 8h;
With
sodium hydroxide;
In
water; acetone;
pH=11 - 11.5;
|
87%
|
|
With
formic acid;
In
water; ethyl acetate;
for 2h;
Heating / reflux;
|
77%
|
|
With
formic acid;
In
chloroform; water;
at 70 ℃;
for 2h;
Inert atmosphere;
|
71%
|
|
With
formic acid;
In
chloroform;
at 70 ℃;
for 4h;
|
57%
|
|
formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A;
With
formic acid;
In
water; acetonitrile;
for 24h;
Heating / reflux;
With
sodium hydroxide;
In
water; acetonitrile;
pH=10.5;
|
|
|
With
formic acid;
In
ethanol;
at 78 ℃;
for 4h;
Industry scale;
|
|
|
formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A;
With
formic acid;
In
chloroform;
for 10h;
pH=5 - 5.5;
Heating / reflux;
With
hydrogenchloride;
In
water;
pH=4;
With
sodium hydroxide;
pH=8;
Product distribution / selectivity;
|
|
|
With
formic acid;
In
chloroform;
for 10h;
pH=5 - 5.5;
Product distribution / selectivity;
Heating / reflux;
|
|
|
formaldehyd; 9-Deoxo-9a-aza-9a-homoerythromycin A;
With
formic acid;
In
acetone;
for 24h;
Reflux;
In
acetone;
pH=10.5;
Alkaline solution;
|
|
|
With
formic acid; triethylamine;
In
acetone;
at 46 - 48 ℃;
for 8h;
|
|
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83905-01-5,92470-27-4
Zithromax(R)
Conditions
| Conditions |
Yield |
|
at 80 ℃;
under 15.0015 Torr;
|
100%
|
2.What is the CAS number for Azithromycin ?
The CAS number of Azithromycin is 83905-01-5.
More information of Azithromycin 83905-01-5 are:
|
CAS Number
|
83905-01-5 |
|
Density
|
1.184 g/cm3 |
|
Melting Point
|
113-115 °C |
|
Boiling Point
|
822.105 °C at 760 mmHg |
|
Flash Point
|
450.993 °C |
|
Vapor Pressure
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2.51E-31mmHg at 25°C |
|
Refractive Index
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1.536 |
|
HS CODE
|
29419090 |
|
PSA
|
180.08000 |
|
LogP
|
1.83860 |
|
Pka
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pKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain) |
3.What are another words for Azithromycin ?
Synonyms for Azithromycin 83905-01-5:Azithromycin [USAN:BAN:INN];Misultina;1-Oxa-6-azacyclopentadecan-15-one,13-[(2,- 6-dideoxy-3-C-methyl-3-O-methyl-R-Lribo- hexopyranosyl)oxy]-2-ethyl-3,4,10- trihydroxy-3,5,6,8,10,12,14-heptamethyl-11- [[3,4,6-trideoxy-3-(dimethylamino)-a-D-xylohexopyranosyl] oxy]-,(2R,3S,4R,5R,8R,10R,11R,- 12S,13S,14R)-;Azithromycin (AIDS Initiative);Hemomycin;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one;9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A;Zithromax;Tobil;Zitrotek;Aritromicina [Spanish];(2R,3R,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one;Azitromax;Azithromycinum [Latin];CP-62993;Setron;Sumamed;Azithromycine [French];Zeto;Zitromax;Aztrin;Zithrax;1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methylhexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-;Zifin;[2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-;Azithromycin? /Azithromycin Dihydrate;Azithromycin Dihydrate;Azithromycin(water soluble);
4.What is the molecular formula of Azithromycin?
The chemical formula of Azithromycin is C38H72N2O12 which containing 38 Carbon atoms,72 Hydrogen atoms,2 Nitrogen atoms and 12 Oxygen atoms,and the molecular weight of Azithromycin is 748.996.
5.What is Azithromycin (83905-01-5) used for?
Azithromycin was the first of the azalides and was designed to improve the stability and biological half-life of erythromycin A, as well as improve activity against Gram negative bacteria. Azithromycin is a long-acting macrolide antibiotic structurally related to erythromycin A (EA), having a methyl-substituted nitrogen at position 9a in the aglycone ring.
InChI:InChI=1/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22-,23-,24+,25-,26+,27+,28-,29-,30+,31-,32+,33+,35+,36-,37-,38+/m1/s1
Relevant articles related to Azithromycin:
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Article
|
Source
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Mild, calcium catalysed Beckmann rearrangements
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Kiely-Collins,Sechi,Brennan,McLaughlin
supporting information, p. 654 - 657 (2018/02/06)
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Preparation method of norazithromycin
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Paragraph 0101; 0102; 0103, (2017/10/26)
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6.Buy Azithromycin with the best price .
weifang yangxu group co.,ltd is a quality supplier of Azithromycin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Azithromycin 83905-01-5.
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