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Erythromycin

  • Product Name: Erythromycin
  • CasNo: 114-07-8
  • Purity:
  • Appearance: white to off white crystalline powder

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CasNo: 114-07-8

Molecular Formula: C37H67NO13

Appearance: white to off white crystalline powder

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1.What is the Erythromycin ?

Erythromycin is an antibiotic in the macrolide family that also has promotility effects because it is a motilin agonist.

Labeled Erythromycin, intended for use as an internal standard for the quantification of Erythromycin by GC- or LC-mass spectrometry.

erythromycin A N-oxide
992-65-4

erythromycin A N-oxide

erythromycin
114-07-8

erythromycin

Conditions
Conditions Yield
With hydrogen; Raney-Ni (W4); In ethanol; at 25 ℃; for 1h;
84%
With hydrogen; Rany Ni (W4); In ethanol; at 25 ℃; for 1h;
84%
erythromycin thiocyanate A
7704-67-8

erythromycin thiocyanate A

erythromycin
114-07-8

erythromycin

Conditions
Conditions Yield
With sodium hydroxide; In methanol; at 40 ℃; pH=9-9.8;
99.33%
With ammonia; In dichloromethane; water; at 25 - 35 ℃;
In dichloromethane; water; at 37 ℃; pH=12; Product distribution / selectivity;
With ammonia; In water; at 35 - 70 ℃; for 1.5h; Reagent/catalyst;
106 g

2.What is the CAS number for Erythromycin ?

The CAS number of Erythromycin is 114-07-8.

More information of Erythromycin 114-07-8 are:

CAS Number

114-07-8

Density

1.209 g/cm3

Melting Point

138-140 °C

Boiling Point

818.401 °C at 760 mmHg

Flash Point

448.753 °C

Vapor Pressure

4.94E-31mmHg at 25°C

Refractive Index

-74 ° (C=2, EtOH)

HS CODE

3004.20

PSA

193.91000

LogP

1.78560

Pka

8.8(at 25℃)

3.What are another words for Erythromycin ?

Synonyms for Erythromycin 114-07-8:Erythromycin A;Erymax;Pentadecanoic acid, 3-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]- 6,11,12,13-tetrahydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-5-[[3,4, 6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, .mu.-lactone, [2R-(2R*,3S*,4S*,5R*,6R*,8R*,10R*,11R*,12S*,13S*)]-;Taimoxin-F;EM;Abomacetin;Abboticin;Erythro;Kesso-Mycin;Erythromid;Erycin;Propiocine;Ilotycin;Prestwick_205;6-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl)oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione;Oxacyclotetradecane-2,10-dione, 4-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]- 14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4, 6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4S*,5R*,6R*,8R*,10R*,11R*,12S*,13S*)]-;

4.What is the molecular formula of Erythromycin?

The chemical formula of  Erythromycin is C37H67NO13 which containing 37 Carbon atoms,67 Hydrogen atoms,1 Nitrogen atoms and 13 Oxygen atoms,and the molecular weight of  Erythromycin is 733.938.

5.What is Erythromycin (114-07-8) used for?

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l). Erythromycin (10-40 mg/kg) dose-dependently inhibits the growth of S. aureus in a mouse model of thigh infection. It also inhibits the cytochrome P450 (CYP450) isoform CYP3A4 in vitro with IC50 values of 33 and 27.3 μM for α-hydroxytriazolam and 4-hydroxytriazolam formation, respectively, following administration of triazolam, which is known to be metabolized primarily by CYP3A4. Formulations containing erythromycin have been used in the treatment of bacterial respiratory and skin infections, pertussis, and a variety of other bacterial infections.

InChI:InChI=1/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21?,22-,23+,24+,25-,26+,28-,29?,30?,31+,32?,34?,35-,36-,37-/m1/s1

Relevant articles related to Erythromycin:

Article

Source

A NOVEL PROCESS OF LIBERATION OF ERYTHROMYCIN AND PREPARATION OF ITS SALTS

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Page/Page column 12, (2014/09/29)

CRYSTALLIZING METHOD OF ERYTHROMYCIN

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Page/Page column 3, (2011/07/30)

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