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CasNo: 864070-44-0
Molecular Formula: C23H27ClO7
Manufacturer supply top purity Empagliflozin 864070-44-0 with ISO standards We provide high quality Empagliflozin (CAS 864070-44-0), at a very affordable prices to our customers.
Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, was originally discovered by Boehringer Ingelheim and codeveloped and co-marketed through research collaboration with Eli Lilly and Co. It was first approved by European Medicine Agency (EMA) in May 2014, followed by the approval of the US FDA in August 2014. SGLT2 inhibitors are anewclass of glucose-lowering agents developed for the treatment of type 2 diabetes mellitus, which have a mechanism of action that is independent of pancreatic b-cell function or the degree of insulin resistance. Consequently, SGLT2 inhibitors have the potential to be of use not only as standalone therapy but also in combination with any of the existing classes of glucose-lowering agents, including insulin. Empagliflozin selectively inhibits SGLT2, which in turn prevents glucose reabsorption by excreting excess glucose in the urine.
Empagliflozin is a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.
The CAS number of Empagliflozin is 864070-44-0.
More information of Empagliflozin 864070-44-0 are:
CAS Number |
864070-44-0 |
Density |
1.398 |
Boiling Point |
665℃ |
Flash Point |
356℃ |
PSA |
108.61000 |
LogP |
1.61340 |
Pka |
13.23±0.70(Predicted) |
The chemical formula of Empagliflozin is C23H27ClO7 which containing 23 Carbon atoms,27 Hydrogen atoms,1 Chlorine atoms and 7 Oxygen atoms,and the molecular weight, and the molecular weight of Empagliflozin is 450.916
Empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, was originally discovered by Boehringer Ingelheim and codeveloped and co-marketed through research collaboration with Eli Lilly and Co. It was first approved by European Medicine Agency (EMA) in May 2014, followed by the approval of the US FDA in August 2014. SGLT2 inhibitors are anewclass of glucose-lowering agents developed for the treatment of type 2 diabetes mellitus, which have a mechanism of action that is independent of pancreatic b-cell function or the degree of insulin resistance. Consequently, SGLT2 inhibitors have the potential to be of use not only as standalone therapy but also in combination with any of the existing classes of glucose-lowering agents, including insulin. Empagliflozin selectively inhibits SGLT2, which in turn prevents glucose reabsorption by excreting excess glucose in the urine.
Relevant articles related to Empagliflozin:
Article |
Source |
IMPROVED PROCESS FOR THE PREPARATION OF EMPAGLIFLOZIN AND ITS CRYSTALLINE POLYMORPH |
- Page/Page column 4; 9-11, (2021/12/31) |
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