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CasNo: 564-25-0
Molecular Formula: C22H24N2O8
Appearance: yellow solid
Factory supply Doxycycline 564-25-0 with sufficient production capacity We supply high quality Doxycycline (CAS 564-25-0), in stock, factory directly supply to clients, lower prices, more competitiveness.
Doxycycline is yellow solid, while it's Molecular Formula is C22H24N2O8. Doxycycline is used for the same indications as other antibiotics of the tetracycline series; however, it belongs to the group of long-lasting tetracyclines. In some cases it is more active with respect to a number of organisms, and is better tolerated than other tetracyclines. Synonyms of this drug are azudoxat, codidoxal, eftapan, vibramycin, and others.
The CAS number of Doxycycline is 564-25-0.
More information of Doxycycline 564-25-0 are:
Synonyms |
2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(6CI,8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5a,5aa,6a,12aa)]-;4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;5-Hydroxy-a-6-deoxytetracycline;6-Deoxy-5-hydroxytetracycline;6-Deoxyoxytetracycline;Dentistar;Deoxymykoin;Dotur;Doximal;Doxinyl;Doxivetin;Doxy RW;Doxy-Gel;Doxycen;Doxycycline;GS 3065;Hydramycin;Liviatin;Medeomycin;Monodox;Oxytetracycline, 6-deoxy-;Pulmodox;Ronaxan;Tolexine;Unidox;Vibramycin;Vibramycine;Vibraveineuse;a-6-Deoxy-5-hydroxytetracycline;a-Doxycycline; |
CAS Number |
564-25-0 |
Molecular Formula |
C22H24N2O8 |
Molecular Weight |
444.441 |
Density |
1.63 g/cm3 |
Melting Point |
206-209 °C |
Boiling Point |
685.2 °C at 760 mmHg |
Flash Point |
368.2 °C |
HS CODE |
3004909090 |
PSA |
181.62000 |
LogP |
0.35270 |
Pka |
pKa 3.5 (Uncertain);7.7 (Uncertain);9.5 (Uncertain) |
Doxycycline, a semi-synthetic tetracycline antibiotic, is derived from the hydrogenolysis of oxytetracycline to remove the 6-hydroxy group. It was first reported in 1958 and released for use in 1967. Doxycycline, along with minocycline, is considered a 'third generation' tetracycline, replacing earlier analogues and pro-drugs for mainstream antibiotic applications. It exhibits broad-spectrum antibacterial and antiprotozoan activity by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Doxycycline is a more recent addition to the tetracycline group of antibiotics, characterized by its stability in acids and bases, long biological half-life, and high absorption from the gastrointestinal tract. It is available in various forms, including hydrate salt, hydrochloride salt, and monohydrate.
InChI:InChI=1/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1
Articles related to Doxycycline:
Article |
Source |
PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS |
- Paragraph 0058; 0218-0219; 0251; 0258-0259, (2020/07/02) |
Solid state chemistry of the antibiotic doxycycline: Structure of the neutral monohydrate and insights into its poor water solubility |
Legendre, Alexandre O.,Silva, Laila R. R.,Silva, Douglas M.,Rosa, Iara M. L.,Azarias, Lilian C.,De Abreu, Polyana J.,De Araujo, Magali B.,Neves, Person P.,Torres, Claudia,Martins, Felipe T.,Doriguetto, Antonio C. experimental part, p. 2532 - 2540 (2012/07/28) |
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